cell-based biosensors have become a research hotspot in biosensors and bioelectronics fields. the main feature of cell-based biosensors is the immobilization of living cell on the surface of transducers. different types of polymers which are used as scaffolds for cell growth should be biocompatible and have reactive functional groups for further attachment of biomolecules. in this work, the cel...

Background: Traditional medicine is inspiring in drug development research. Epilobium parviflorum extracts have shown promising therapeutic effects on prostate cancer cells. The similarities between breast and prostate cancers at molecular and metabolic levels prompted us to explore its effects on human breast cancer. Methods: The root, aerial parts and flowers of the plant were, collected and...

Objective: Biebersteinia (Geraniaceae) has a history of use in traditional medicine in some countries including Iran. In the present study, cytotoxic and apoptogenic properties of hydro-ethanol extract of B. multifidi was investigated on human prostate cancer cell lines (PC3 and DU 145) and human embryonic kidney 293 (HEK293) cells. Materials and Methods: Cells were cultured in RPMI-1640 medium...

the present study was carried out to investigate cytotoxic activity of flower, leaf, stem and root extracts of five artemisia species against breast cancer cell line (mcf7) and human embryonic kidney normal cell line (hek293). the studied artemisia species were a. absinthium , a. vulgaris , a. incana , a. fragrans and a. spicigera . the cytotoxic activity was measured by mtt assay at different ...

objective: biebersteinia (geraniaceae) has a history of use in traditional medicine in some countries including iran. in the present study, cytotoxic and apoptogenic properties of hydro-ethanol extract of b. multifidi was investigated on human prostate cancer cell lines (pc3 and du 145) and human embryonic kidney 293 (hek293) cells. materials and methods: cells were cultured in rpmi-1640 medium...

Background: Research on animal toxins have shown toxicity potential cancerous cell and tissues in the cultures. Conotoxins obtained from marine cone snails show highest potential, so that several human deaths been attributed to this species of snail. These proven be valuable agents inhibit enzymes, channels proteins, nervous systems humans. Methods: We studied effects Conus textile crude venom ...

Newcastle disease virus (NDV) exhibits oncolysis in its natural form. This oncolytic (OV) has the potential to specifically infect, propagate, and lyse cancer cells while sparing normal cells. study was aimed screen for NDV strain isolated from poultry. A total of ten velogenic strains were propagated 10 day old embryonated SPF chicken eggs allantoic fluid these infected collected further study...

BACKGROUND Exposure to cadmium is associated with human pathologies and altered gene expression. The molecular mechanisms by which cadmium affects transcription remain unclear. It has been proposed that cadmium activates transcription by altering intracellular calcium concentration ([Ca(2+)](i)) and disrupting calcium-mediated intracellular signaling processes. This hypothesis is based on sever...